BOTOX® Therapeutic—About BOTOX® Injections

Signs of Cervical Dystonia

Medical Uses of BOTOX^®

How BOTOX^® Works

BOTOX^® History

Important Safety Information

Can BOTOX^® Help You?

What to Expect and Safety

Helpful Resources

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About BOTOX®

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BOTOX^® neurotoxin is a medicine approved to treat:

Cervical dystonia (CD)—head tilting, neck pain, and neck muscle spasms
- CD is also known as spasmodic torticollis
Blepharospasm, or eyelid spasms
Strabismus, also called crossed eyes
Severe underarm sweating when antiperspirants don’t work
- For more information, visit www.BOTOXSevereSweating.com

Living with these conditions can be difficult. They can even make it hard to do simple daily tasks, such as dressing yourself or driving a car. But with treatment, you may be able to manage your symptoms. Many people have turned to BOTOX^® for relief with positive results.

BOTOX^® treatment is given by injection. Only a licensed doctor can give patients BOTOX^® injections. Allergan ensures strict quality control when manufacturing BOTOX^®. The source of BOTOX^® is a type of bacteria called Clostridium botulinum. These bacteria produce a substance that is the active ingredient in BOTOX^®.

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Next: Medical Uses of BOTOX^®

BOTOX^® is indicated for the treatment of cervical dystonia in adults to decrease the severity of abnormal head position and neck pain associated with cervical dystonia.

BOTOX^® is indicated for the treatment of strabismus (crossed eyes) and blepharospasm (eyelid spasms) associated with dystonia (muscle tightening), including benign essential blepharospasm of VII nerve disorders in patients 12 years of age and above.

The efficacy of BOTOX^® treatment in deviations over 50 prism diopters, in restrictive strabismus, in Duane's syndrome with lateral rectus weakness, and in secondary strabismus caused by prior surgical over-recession of the antagonist has not been established. BOTOX^® is ineffective in chronic paralytic strabismus except when used in conjunction with surgical repair to reduce antagonist contracture.

IMPORTANT SAFETY INFORMATION

BOTOX^® injections should not be given to people who have an infection where the physician proposes to inject. They should not be given to people who are known to be sensitive to any ingredient in BOTOX^® product.

Serious heart problems and serious allergic reactions have been reported rarely. If you think you’re having an allergic reaction or other unusual symptoms, such as difficulty swallowing, speaking or breathing, call your doctor immediately.

Patients with certain neuromuscular disorders such as ALS, myasthenia gravis or Lambert-Eaton syndrome may be at increased risk of serious side effects.

In cervical dystonia, the most common side effects following injection include difficulty swallowing, upper respiratory infection, neck pain and headache.

In blepharospasm, the most common side effects following injection include ptosis, inflammation of the cornea and eye dryness.

In strabismus, the most common side effects following injection include ptosis and vertical deviation.

Please see full prescribing information for BOTOX^®.

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